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1

“Toxic memory” via chaperone modification is a potential mechanism for rapid mallory-denk body reinduction

Pavel Strnad, Guo-Zhong Tao, Phillip So, Kenneth Lau, Jim Schilling, Yuquan Wei, Jian Liao, M. Bishr Omary

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 5.05 MB

english, 2008

2

From Mallory to Mallory–Denk bodies: What, how and why?

Kurt Zatloukal, Samuel W. French, Cornelia Stumptner, Pavel Strnad, Masaru Harada, Diana M. Toivola, Monique Cadrin, M. Bishr Omary

Journal:

Experimental Cell Research

Année:

2007

Langue:

english

Fichier:

PDF, 7.77 MB

english, 2007

3

‘Hard’ and ‘soft’ principles defining the structure, function and regulation of keratin intermediate filaments

Pierre A Coulombe, M.Bishr Omary

Journal:

Current Opinion in Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 175 KB

english, 2002

4

Cell biology to disease and back

Omary, M. Bishr

Journal:

Nature Reviews Molecular Cell Biology

Année:

2015

Langue:

english

Fichier:

PDF, 119 KB

english, 2015

5

Review series Toward unraveling the complexity of simple epithelial keratins in human disease

Omary, M Bishr, Ku, Nam-on, Strnad, Pavel, Hanada, Shinichiro

Année:

2009

Langue:

english

Fichier:

PDF, 2.54 MB

english, 2009

6

Not All Mice Are the Same: Standardization of Animal Research Data Presentation

Omary, M Bishr, Cohen, David E, El-Omar, Emad, Jalan, Rajiv, Low, Malcolm, Nathanson, Michael, Peek, Richard, Turner, Jerrold

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 506 KB

english, 2016

7

The hepatic BMAL1/AKT/Lipogenesis axis protects against alcoholic liver disease via promoting PPARα pathway

Zhang, Deqiang, Tong, Xin, Nelson, Bradley B., Jin, Ethan, Sit, Julian, Charney, Nicholas, Yang, Meichan, Omary, M. Bishr, Yin, Lei

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2018

8

Keratins provide virus-dependent protection or predisposition to injury in coxsackievirus-induced pancreatitis

Toivola, Diana, Omary, M. Bishr, Ramsingh, Arlene, Magin, TM, Ostrowski,, Baribault, Helen, Toivola, Diana

Journal:

Cell Health and Cytoskeleton

Année:

2009

Langue:

english

Fichier:

PDF, 18.21 MB

english, 2009

9

Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury

Maitra, Dhiman, Bragazzi Cunha, Juliana, Elenbaas, Jared S., Bonkovsky, Herbert L., Shavit, Jordan A., Omary, M. Bishr

Journal:

CMGH Cellular and Molecular Gastroenterology and Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2019

10

Multifocal heterogeneity in villin and Ep-CAM expression in Barrett's esophagus

Sarita Kumble, M. Bishr Omary, Luis F. Fajardo, George Triadafilopoulos

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 921 KB

english, 1996

11

Aggregation and loss of cytokeratin filament networks inhibit Golgi organization in liver-derived epithelial cell lines

Hiroto Kumemura, Masaru Harada, M. Bishr Omary, Shotaro Sakisaka, Tatsuo Suganuma, Masayoshi Namba, Michio Sata

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2004

12

Method of cell handling affects leakiness of cell surface labeling and detection of intracellular keratins

Carrie L. Riopel, Isha Butt, Dr. M. Bishr Omary

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.33 MB

english, 1993

13

Two-dimensional gel analysis of glandular keratin intermediate filament phosphorylation

Jiam Liao, Nam-on Ku, Dr. M. Bishr Omary

Journal:

ELECTROPHORESIS

Année:

1996

Langue:

english

Fichier:

PDF, 627 KB

english, 1996

14

Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease

Diana M. Toivola, Nam-On Ku, Evelyn Z. Resurreccion, David R. Nelson, Teresa L. Wright, M. Bishr Omary

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 351 KB

english, 2004

15

Keratin mutation primes mouse liver to oxidative injury

Qin Zhou, Xuhuai Ji, Lixin Chen, Harry B. Greenberg, Shelly C. Lu, M. Bishr Omary

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 301 KB

english, 2005

16

Keratin variants associate with progression of fibrosis during chronic hepatitis C infection

Pavel Strnad, Tim C. Lienau, Guo-Zhong Tao, Laura C. Lazzeroni, Felix Stickel, Detlef Schuppan, M. Bishr Omary

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 845 KB

english, 2006

17

Keratin 18 overexpression but not phosphorylation or filament organization blocks mouse Mallory body formation

Masaru Harada, Pavel Strnad, Evelyn Z. Resurreccion, Nam-On Ku, M. Bishr Omary

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2007

18

Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies

Nam-On Ku, Pavel Strnad, Bi-Hui Zhong, Guo-Zhong Tao, M. Bishr Omary

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2007

19

Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation

Masaru Harada, Shinichiro Hanada, Diana M. Toivola, Nafisa Ghori, M. Bishr Omary

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 3.68 MB

english, 2008

20

The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury

Shinichiro Hanada, Pavel Strnad, Elizabeth M. Brunt, M. Bishr Omary

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2008

21

Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity

Bihui Zhong, Pavel Strnad, Carlo Selmi, Pietro Invernizzi, Guo-Zhong Tao, Angela Caleffi, Minhu Chen, Ilaria Bianchi, Mauro Podda, Antonello Pietrangelo, M. Eric Gershwin, M. Bishr Omary

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 890 KB

english, 2009

22

Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: Heparin prevents and treats liver damage

Sujith V. W. Weerasinghe, David S. Moons, Peter J. Altshuler, Yatrik M. Shah, M. Bishr Omary

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2011

23

Protein phosphatase inhibition in normal and keratin 8/18 assembly–incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity

Diana M. Toivola, M. Bishr Omary, Nam-on Ku, Olli Peltola, Hélène Baribault, John E. Eriksson

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 2.20 MB

english, 1998

24

Denaturing temperature selection may underestimate keratin mutation detection by DHPLC

Pavel Strnad, Tim Christian Lienau, Guo-Zhong Tao, Nam-On Ku, Thomas M. Magin, M. Bishr Omary

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 407 KB

english, 2006

25

Biochemical and morphological differentiation of the human colonic epithelial cell line SW620 in the presence of dimethylsulfoxide

Dr. M. Bishr Omary, Louise de Grandpre, Michael McCaffrey, Martin F. Kagnoff

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 813 KB

english, 1992

26

Chemistry and Biology of Dihydroisoxazole Derivatives: Selective Inhibitors of Human Transglutaminase 2

Kihang Choi, Matthew Siegel, Justin L. Piper, Liya Yuan, Eun Cho, Pavel Strnad, Bishr Omary, Keith M. Rich, Chaitan Khosla

Journal:

Chemistry & Biology

Année:

2005

Langue:

english

Fichier:

PDF, 163 KB

english, 2005

27

Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure

Ying Hao, Sumita Sood, George Triadafilopoulos, Jong Hyeok Kim, Zheng Wang, Peyman Sahbaie, M Bishr Omary, Anson W Lowe

Journal:

BMC Gastroenterology

Année:

2007

Langue:

english

Fichier:

PDF, 970 KB

english, 2007

28

Implications of intermediate filament protein phosphorylation

Nam-On Ku, Jian Liao, Chih-Fong Chou, M. Bishr Omary

Journal:

Cancer and Metastasis Reviews

Année:

1996

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1996

29

Structural heterogeneity of human Pgp-1 and its relationship with p85

M. Bishr Omary, Ian S. Trowbridge, Michelle Letarte, Martin F. Kagnofe, Clare M. Isacke

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 515 KB

english, 1988

30

Human cell-surface glycoprotein with unusual properties

Omary, M. Bishr, Trowbridge, Ian S., Minowada, Jun

Journal:

Année:

1980

Fichier:

PDF, 636 KB

1980

31

Cell biology: Skin care by keratins

Omary, M. Bishr, Ku, Nam-On

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 215 KB

english, 2006

32

Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells

Beil, Michael, Micoulet, Alexandre, von Wichert, Götz, Paschke, Stephan, Walther, Paul, Omary, M. Bishr, Van Veldhoven, Paul P., Gern, Ulrike, Wolff-Hieber, Elke, Eggermann, Juliane

Journal:

Nature Cell Biology

Année:

2003

Langue:

english

Fichier:

PDF, 6.28 MB

english, 2003

33

Cytoskeletal keratin glycosylation protects epithelial tissue from injury

Ku, Nam-On, Toivola, Diana M., Strnad, Pavel, Omary, M. Bishr

Journal:

Nature Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2010

34

Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18

Diana M. Toivola, Mikko I. Nieminen, Michael Hesse, Tao He, H[eacute]l[egrave]ne Baribault, Thomas M. Magin, M.Bishr Omary, John E. Eriksson

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2001

35

Keratins: Guardians of the liver

M.Bishr Omary, Nam-On Ku, Diana M. Toivola

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 359 KB

english, 2002

36

Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury

Nam-On Ku, Roy M. Soetikno, M.Bishr Omary

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 676 KB

english, 2003

37

Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins

Ku, Nam-On, Liao, Jian, Omary, M.Bishr

Journal:

The EMBO Journal

Année:

1998

Langue:

english

Fichier:

PDF, 884 KB

english, 1998

38

Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria

Amika Singla, David S. Moons, Natasha T. Snider, Elizabeth R. Wagenmaker, V. Bernadene Jayasundera, M. Bishr Omary

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2012

39

Cellular integrity plus: organelle-related and protein-targeting functions of intermediate filaments

Diana M. Toivola, Guo-Zhong Tao, Aida Habtezion, Jian Liao, M. Bishr Omary

Journal:

Trends in Cell Biology

Année:

2005

Langue:

english

Fichier:

PDF, 375 KB

english, 2005

40

‘Heads and tails’ of intermediate filament phosphorylation: multiple sites and functional insights

M. Bishr Omary, Nam-On Ku, Guo-Zhong Tao, Diana M. Toivola, Jian Liao

Journal:

Trends in Biochemical Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 392 KB

english, 2006

41

Special issue: Intermediate filaments

M. Bishr Omary, Harald Herrmann, Urban Lendahl

Journal:

Experimental Cell Research

Année:

2007

Langue:

english

Fichier:

PDF, 148 KB

english, 2007

42

A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice

Michael Hesse, Christine Grund, Harald Herrmann, Dominique Bröhl, Thomas Franz, M. Bishr Omary, Thomas M. Magin

Journal:

Experimental Cell Research

Année:

2007

Langue:

english

Fichier:

PDF, 4.43 MB

english, 2007

43

Hepatocyte-derived cultured cells with unusual cytoplasmic keratin-rich spheroid bodies

Pierre-Yves Delavalle, Khaled Alsaleh, André Pillez, Laurence Cocquerel, Cécile Allet, Patrick Dumont, Anne Loyens, Emmanuelle Leteurtre, M. Bishr Omary, Jean Dubuisson, Yves Rouillé, Czeslaw Wychowsk

Journal:

Experimental Cell Research

Année:

2011

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2011

44

Expression, Glycosylation, and Phosphorylation of Human Keratins 8 and 18 in Insect Cells

Nam-On Ku, M.Bishr Omary

Journal:

Experimental Cell Research

Année:

1994

Fichier:

PDF, 1.52 MB

1994

45

Heat Stress or Rotavirus Infection of Human Epithelial Cells Generates a Distinct Hyperphosphorylated Form of Keratin 8

Jian Liao, Lori A. Lowthert, M.Bishr Omary

Journal:

Experimental Cell Research

Année:

1995

Fichier:

PDF, 1.03 MB

1995

46

Effects of Keratin Filament Disruption on Exocrine Pancreas-Stimulated Secretion and Susceptibility to Injury

Diana M. Toivola, Nam-On Ku, Nafisa Ghori, Anson W. Lowe, Sara A. Michie, M.Bishr Omary

Journal:

Experimental Cell Research

Année:

2000

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2000

47

Reciprocal keratin 18 Ser48 O-GlcNAcylation and Ser52 phosphorylation using peptide analysis

Guo-Zhong Tao, Celeste Kirby, Stephen A. Whelan, Frank Rossi, Xiahui Bi, Michael MacLaren, Erik Gentalen, Roger A. O’Neill, Gerald W. Hart, M. Bishr Omary

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 311 KB

english, 2006

48

Pharmacologic transglutaminase inhibition attenuates drug-primed liver hypertrophy but not Mallory body formation

Pavel Strnad, Matthew Siegel, Diana M. Toivola, Kihang Choi, Jon C. Kosek, Chaitan Khosla, M. Bishr Omary

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2006

49

Oxidative stress induces the endoplasmic reticulum stress and facilitates inclusion formation in cultured cells

Shinichiro Hanada, Masaru Harada, Hiroto Kumemura, M. Bishr Omary, Hironori Koga, Takumi Kawaguchi, Eitaro Taniguchi, Takafumi Yoshida, Takao Hisamoto, Chikatoshi Yanagimoto, Michiko Maeyama, Takato U

Journal:

Journal of Hepatology

Année:

2007

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2007

50

Keratin 8/18 breakdown and reorganization during apoptosis

Bert Schutte, Mieke Henfling, Wendy Kölgen, Maartje Bouman, Stephan Meex, Mathie P.G Leers, Marius Nap, Viveka Björklund, Peter Björklund, Bertil Björklund, E.Birgitte Lane, M.Bishr Omary, Hans Jörnva

Journal:

Experimental Cell Research

Année:

2004

Langue:

english

Fichier:

PDF, 783 KB

english, 2004